SciELO - Brasil - Progranulin (PGRN) is serves as an inflammation-response biomarker and promotes lung damage in burn-induced Sepsis via the SIRT1 Pathways by ROS Progranulin (PGRN) is serves as an inflammation-response
Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice | EMBO reports
The Role of Progranulin (PGRN) in the Pathogenesis of Ischemic Stroke | SpringerLink
Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis | Nature Communications
Progranulin as a therapeutic target in neurodegenerative diseases: Trends in Pharmacological Sciences
PGRN interactions, trafficking, and proteolysis. Several PGRN receptors... | Download Scientific Diagram
A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses | Life Science Alliance
Induced Pluripotent Stem Cell Models of Progranulin-Deficient Frontotemporal Dementia Uncover Specific Reversible Neuronal Defects - ScienceDirect
New insights and therapeutic opportunities for progranulin-deficient frontotemporal dementia - ScienceDirect
Schematic diagram of the progranulin (PGRN) mechanism in HUVECs.... | Download Scientific Diagram
Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17 | Nature
Frontiers | Parkin Levels Decrease in Fibroblasts With Progranulin (PGRN) Pathogenic Variants and in a Cellular Model of PGRN Deficiency
Lysosomal functions of progranulin and implications for treatment of frontotemporal dementia - ScienceDirect
Progranulin in frontotemporal lobar degeneration and neuroinflammation | Journal of Neuroinflammation | Full Text
Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRN Mutations | eNeuro
Progranulin axis and recent developments in frontotemporal lobar degeneration | Alzheimer's Research & Therapy | Full Text